Investigator's Brochure (IB) Table

Drugs

Drug Name Sort ascending Drug Company IB Date Risk List Available?
Vorinostat (Zolinza) Merck August 2013
Tenofovir Vaginal Ring CONRAD August 2017
Tenofovir Gel CONRAD January 2013
Tenofovir Alafenamide/Elvitegravir CONRAD July 2019
Sofosbuvir/Velapatasvir (Epclusa) Gilead July 2016
Rilpivirine (TMC278, Edurant) Janssen Research & Development July 2019
Rifapentine Sanofi August 2013
Raltegravir (Isentress) Merck September 2017 YES
PC-1005 Population Council April 2017
Maraviroc (UK-427857) ViiV Healthcare October 2017
HEC Placebo Gel CONRAD September 2011
GSK1265744 (Cabotegravir) ViiV Healthcare December 2018
Glecaprevir (ABT-493) and Pibrentasvir (ABT-530) AbbVie December 2018
Etravirine (TMC125, Intelence) - New Janssen Research & Development November 2019
Emtricitabine/Tenofovir Disoproxil Fumarate (Truvada) Gilead Sciences December 2016 YES
Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (MK-1439A) Merck May 2019
Doravirine (MK-1439) Merck May 2019
Dolutegravir (GSK1349572) - New ViiV Healthcare November 2019
Delamanid (OPC-67683) Otsuka April 2019
Dapivirine (Vaginal Ring) - New International Partnership For Microbicides November 2019

Vaccines

Vaccine Name Vaccine Company IB Date Risk List Available?
Hepatitis B Vaccine Recombinant, Adjuvanted (Heplisav-B) - New Dynavax Technologies Corporation August 2019
PGT121.414.LS (VRC-HIVMAB0107-00-AB) - New VCMP/NIAID/NIH October 2019
BG505 SOSIP.664 gp140 - New DAIDS/NIAID/NIH October 2019
B63521^11 gp120 DAIDS/NIAID/NIH July 2019
MPER-656 Liposomes with Aluminum Hydroxide Suspension DAIDS/NIAID/NIH February 2019
PGDM1400 Beth Israel Deaconess Medical Center August 2018
PGT121 Beth Israel Deaconess Medical Center January 2019
RSV 6120/DeltaNS2/1030s LID/NIAID/NIH March 2019
CH505TF gp120 Transient DAIDS/NIAID/NIH December 2018
GEO-D02 and MVA-HIV62B Vaccine GeoVax June 2019
SAR441236 Sanofi June 2018
10-1074 - New Rockerfeller University/Mass Biologics September 2019
PDPHV-201401 Laboratory of Nucleic Acid Vaccines (LNAV) October 2017
ALVAC-HIV (vCP2438) Sanofi Pasteur August 2017
AIDSVAX B/E Global Solutions for Infectious Diseases March 2016
Ad26.ENVA.01 Crucell Holland BV June 2013
Recombinant oligomeric gp145 C.6980 Clade C HIV Env protein NIH/NIAID August 2017
RSV 276 LID/NIAID/NIH February 2019
Bivalent Subtype C gp120 with Aluminum Hydroxide Adjuvant NIAID/NIH June 2015
RSV DeltaNS2-Delta1313-I1314L LID/NIAID/NIH February 2019