Find a Clinical Trial
Help NIAID help people who are suffering from chronic, serious, or life-threatening illnesses by volunteering for NIAID clinical studies. See the list of featured NIAID clinical trials below or view the complete list of NIAID studies recruiting participants on ClinicalTrials.gov.
NIH investigators are conducting clinical research studies to learn more about what causes food allergy, what can be done to improve the care of patients with food allergy, and how to improve the ways food allergy is diagnosed and treated.
NIAID is committed to advancing the understanding of how and why autoimmune diseases such as rheumatoid arthritis occur.
This study aims to establish whether defects in immune cell function are shared across multiple autoimmune diseases and whether those problems match to similar genes in the cells. Researchers want to learn why some people with asthma need to take a lot more medication than other people with the disease.
Children and adults with type 1 diabetes and their family members may be eligible to participate in clinical trials being conducted across the United States.
Eczema (Atopic Dermatitis)
People with eczema may be particularly susceptible to bacterial, viral, and fungal skin infections. NIAID research increases our understanding of how the immune system contributes to the development of atopic dermatitis, explores the genetic determinants of eczema, and evaluates new strategies to prevent and treat the disease.
This study tests a new approach to therapy using live bacteria (also called a probiotic). NIAID researchers will introduce the bacteria Roseomonas mucosa from healthy skin onto the skin of someone with atopic dermatitis to see if it helps to treat the disease.
NIAID is conducting and supporting research to find new and improved ways to diagnose, treat and prevent influenza (flu) infection. You can join the fight against influenza by volunteering to participate in a clinical study. There is no charge for study-related medical care, including study visits, medications, treatments, and procedures. Volunteers may be compensated for time and travel.
Fungi are everywhere. Most fungi are not dangerous, but some types can be harmful to health, and people with deficient immune systems are more vulnerable to symptomatic infection. NIAID researchers are exploring how fungal susceptibility and infection impact the function of immune cells.
You can help NIAID advance hepatitis research by volunteering to participate in a clinical study.
A small group of people who are HIV positive remain healthy for long periods of time without medications. These Long-Term Non-Progressors have properties within their immune systems that control the virus and can help researchers determine how their immune systems control HIV disease.
NIAID is committed to conducting the research necessary to confront HIV/AIDS. Volunteer participation in a clinical research study helps NIAID better understand HIV, find promising new tools to prevent HIV infection including a vaccine, and develop new and more effective treatment strategies.
Chronic granulomatous disease (CGD) is a genetic disorder in which white blood cells called phagocytes are unable to kill certain types of bacteria and fungi. People with CGD are highly susceptible to infections, such as Staphylococcus aureus, Serratia marcescens, Burkholderia cepacia, Nocardia species, and Aspergillus species. NIAID aims to improve diagnosis, explore new treatments and preventions, and facilitate genetic counseling for this primary immune deficiency disease.
People with hyper-immunoglobulin E syndrome (HIES), aka Job’s Syndrome, have recurrent infections of the skin and lungs caused by bacteria. NIAID-supported research seeks to determine the effect of Job’s Syndrome on the immune system, including which immune cells and responses are affected and how these abnormalities translate into patients’ symptoms.
Urticaria is an itchy skin disorder that may occur spontaneously or after exposure to a physical trigger. This NIAID study is investigating why some people get hives after physical triggers such as cold, heat, water, exercise, pressure or vibration.
This study evaluates the safety and effectiveness of the drug ustekinumab for people with common variable immunodeficiency (CVID) with gastrointestinal inflammation. Ustekinumab is currently approved by the FDA to treat other autoimmune disorders.
Inflammatory Bowel Diseases
The goals of this NIAID study are to learn more about genetic and immune factors that contribute to inflammatory bowel disease and gather information that may lead to better treatment options.
Lupus is an autoimmune disease characterized by inflammation of different tissues of the body. The most common type of lupus is systemic lupus erythematosus (SLE). Women are at far greater risk than men of developing lupus, and SLE disproportionately affects minority populations.
If you suspect that you have Lyme disease, you may be eligible to participate in an NIAID research study.
This NIAID study is investigating why some people who are healthy and have normal immune function become infected with cryptococcosis.
Eosinophilic esophagitis, or EoE, is a chronic disease that can be associated with food allergies. NIAID’s research on EoE and other disorders related to food allergy may provide insight into new treatments and prevention options.
The FUNGI study is looking for people who have developed invasive fungal infections (IFIs), such as aspergillosis, without any prior immune system problems and people with autoimmune endocrinopathy-candidiasis-ectodermal dystrophy (APECED) syndrome.
This study seeks patients who are thought to have normal immune systems, but who have been diagnosed with a viral infection that is unusually severe, prolonged, or persistent. This study will evaluate the participants’ immune systems to determine why the infection developed.