Investigator's Brochure (IB) Table

Drugs

Drug Name Drug Company IB Date Sort descending Risk List Available?
HEC Placebo Gel CONRAD September 2011
Tenofovir Gel CONRAD January 2013
Rifapentine Sanofi August 2013
Vorinostat (Zolinza) Merck August 2013
Sofosbuvir/Velapatasvir (Epclusa) Gilead July 2016
Emtricitabine/Tenofovir Disoproxil Fumarate (Truvada) Gilead Sciences December 2016 YES
PC-1005 Population Council April 2017
Dapivirine (Microbicide Gel) International Partnership for Microbicides May 2017
ABT-267, ABT 333, ABT-450 and Ritonavir AbbVie June 2017
Tenofovir Vaginal Ring CONRAD August 2017
Raltegravir (Isentress) Merck September 2017 YES
Maraviroc (UK-427857) ViiV Healthcare October 2017
Etravirine (TMC125, Intelence) Janssen Research & Development April 2018
Dapivirine (Vaginal Ring) International Partnership For Microbicides July 2018
Dolutegravir (GSK1349572) ViiV Healthcare November 2018
Glecaprevir (ABT-493) and Pibrentasvir (ABT-530) - New AbbVie December 2018
GSK1265744 (Cabotegravir) ViiV Healthcare December 2018
Bedaquiline (TMC207) Janssen Research & Development February 2019
Delamanid (OPC-67683) Otsuka April 2019
Doravirine (MK-1439) - New Merck May 2019

Vaccines

Vaccine Name Vaccine Company IB Date Sort descending Risk List Available?
GEO-D03 and MVA-HIV62B Vaccines (Preventative) GeoVax June 2013
Ad26.ENVA.01 Crucell Holland BV June 2013
DNA-HIV-PT123/NYVAC-HIV-PT1/NYVAC-HIV-PT4 vaccine IPPOX/EuroVacc August 2013
Bivalent Subtype C gp120 with Aluminum Hydroxide Adjuvant NIAID/NIH June 2015
rVSV HIV Vaccines Profectus BioSciences January 2016
AIDSVAX B/E Global Solutions for Infectious Diseases March 2016
Bivalent Subtype C gp120/AS01B GlaxoSmithKline July 2016
DNA Mosaic-Tre env DNA Vaccine DAIDS/NIAID/NIH July 2016
Bivalent Subtype C gp120/MF59 GlaxoSmithKline July 2016
PENNVAX-GP and IL-12 DNA Inovio Parmaceuticals December 2016
DNA CON-S env DAIDS/NIAID/NIH June 2017
ALVAC-HIV (vCP2438) Sanofi Pasteur August 2017
Recombinant oligomeric gp145 C.6980 Clade C HIV Env protein NIH/NIAID August 2017
VRC-HIVMAB080-00-AB (VRC01LS) VRC/NIAID August 2017
PDPHV-201401 Laboratory of Nucleic Acid Vaccines (LNAV) October 2017
p24CE1/2 multivalent pDNA Vaccine expressing HIV M Group p24 Gag and p55 gag pDNA with IL-12 pDNA NCI/NIAID/NIH November 2017
MVA-CMDR Walter Reed Army Institute Research (WRAIR) February 2018
VRC-HIVMAB075-00-AB (VRC07-523LS) VRC/NIAID/NIH February 2018
SAR441236 Sanofi June 2018
PGDM1400 Beth Israel Deaconess Medical Center August 2018