Investigator's Brochure (IB) Table

Drugs

Drug Name Drug Company IB Date Sort descending Risk List Available?
Tenofovir Gel CONRAD January 2013
Rifapentine Sanofi August 2013
Vorinostat (Zolinza) Merck August 2013
Sofosbuvir/Velapatasvir (Epclusa) Gilead July 2016
Emtricitabine/Tenofovir Disoproxil Fumarate (Truvada) Gilead Sciences December 2016 YES
PC-1005 Population Council April 2017
Dapivirine (Microbicide Gel) International Partnership for Microbicides May 2017
ABT-267, ABT 333, ABT-450 and Ritonavir AbbVie June 2017
Tenofovir Vaginal Ring CONRAD August 2017
Raltegravir (Isentress) Merck September 2017 YES
Glecaprevir (ABT-493) and Pibrentasvir (ABT-530) AbbVie December 2018
Tenofovir Alafenamide/Elvitegravir CONRAD July 2019
Bedaquiline (TMC207) Janssen Research & Development October 2019
Dapivirine (Vaginal Ring) International Partnership For Microbicides November 2019
Etravirine (TMC125, Intelence) Janssen Research & Development November 2019
GSK1265744 (Cabotegravir) ViiV Healthcare December 2019
Doravirine (MK-1439) Merck January 2020
Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (MK-1439A) Merck January 2020
Cenicriviroc Mesylate CVC (TBR-652) Allergan March 2020
Delamanid (OPC-67683) Otsuka April 2020

Vaccines

Vaccine Name Vaccine Company IB Date Sort descending Risk List Available?
Ad26.ENVA.01 Crucell Holland BV June 2013
GEO-D03 and MVA-HIV62B Vaccines (Preventative) GeoVax June 2013
DNA-HIV-PT123/NYVAC-HIV-PT1/NYVAC-HIV-PT4 vaccine IPPOX/EuroVacc August 2013
Bivalent Subtype C gp120 with Aluminum Hydroxide Adjuvant NIAID/NIH June 2015
rVSV HIV Vaccines Profectus BioSciences January 2016
AIDSVAX B/E Global Solutions for Infectious Diseases March 2016
Bivalent Subtype C gp120/AS01B GlaxoSmithKline July 2016
DNA Mosaic-Tre env DNA Vaccine DAIDS/NIAID/NIH July 2016
Bivalent Subtype C gp120/MF59 GlaxoSmithKline July 2016
PENNVAX-GP and IL-12 DNA Inovio Parmaceuticals December 2016
DNA CON-S env DAIDS/NIAID/NIH June 2017
Recombinant oligomeric gp145 C.6980 Clade C HIV Env protein NIH/NIAID August 2017
ALVAC-HIV (vCP2438) Sanofi Pasteur August 2017
PDPHV-201401 Laboratory of Nucleic Acid Vaccines (LNAV) October 2017
p24CE1/2 multivalent pDNA Vaccine expressing HIV M Group p24 Gag and p55 gag pDNA with IL-12 pDNA NCI/NIAID/NIH November 2017
HIV-1 Multiantigen pDNA Vaccine and Human IL-12 pDNA Profectus BioSciences August 2018
PGDM1400 Beth Israel Deaconess Medical Center August 2018
CH505TF gp120 Transient DAIDS/NIAID/NIH December 2018
DNA-HIV-PT123 IPPOX January 2019
MPER-656 Liposomes with Aluminum Hydroxide Suspension DAIDS/NIAID/NIH February 2019