Rilpivirine (Edurant) Risk List

The following serious and life-threatening side effects have been associated with the use of rilpivirine:

• Severe skin rash and allergic reactions. If you get a rash with any of the following symptoms, stop taking RPV and call the study doctor or your healthcare provider right away:
  • Fever
  • Blistering on the skin or ulcers/sores in the mouth
  • Eye redness or
  • Swelling of the face, mouth, tongue, throat or other parts of the body

• Depression or mood changes. Tell your healthcare provider right away if you have any of the following symptoms:
  • Feeling sad or hopeless
  • Feeling anxious or restless
  • Have thoughts of hurting yourself (suicide) or have tried to hurt yourself.

• Liver problems:
  • Yellowing of your skin or the whites of your eyes
  • Dark urine (looks like tea))
  • Light-colored bowel movements
  • Loss of appetite
  • Nausea/vomiting
  • Pain, aching, or tenderness in the right side of your stomach (abdominal) area
  • Your healthcare provider may inform you that you have an elevated liver-related function test. People with a history of liver disease may have an increased risk of liver problems.
    
     

Additional side effects may include:

• Headache
• Trouble sleeping
• Feeling tired