Parameter Level Summary of Changes for the Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Event

The Division of AIDS Table for grading the severity of Adult and Pediatric Adverse Events (DAIDS AE Grading Table) is a collection of commonly encountered adverse events and their descriptive terminology utilized for severity grading. As part of its standard review processes, DAIDS reassessed the “DAIDS AE Grading Table, version 2.0” for accuracy and updated it (version 2.1) to be consistent with current NIAID (DAIDS) requirements. Moreover, this document (version 2.1) provides the needed clarifications sought by site investigators, Operations Offices, Statistical and Data Management Centers, and Medical Officers within the Division for some of the parameters. The clarifications and updates have been summarized in the introduction and are also highlighted within the body of the Table for convenience.