Investigator's Brochure (IB) Table

Drugs

Drug Name Sort descending Drug Company IB Date Risk List Available?
ABT-267, ABT 333, ABT-450 and Ritonavir AbbVie June 2017
Bedaquiline (TMC207) Janssen Research & Development October 2024
Dapivirine (Vaginal Ring) International Partnership For Microbicides May 2024
Delamanid (OPC-67683) Otsuka August 2024
Dolutegravir (GSK1349572) ViiV Healthcare October 2024
Doravirine (MK-1439) and Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate (MK-1439A) Merck July 2021
Emtricitabine/Tenofovir Disoproxil Fumarate (Truvada) Gilead Sciences December 2016 YES
Glecaprevir/Pibrentasvir - New - New AbbVie January 2024
GSK1265744 (Cabotegravir) ViiV Healthcare January 2025
Pretomanid (PA-824) Global Alliance for TB Drug Development (TB Alliance) November 2023
Remdesivir (Veklury) Gilead Sciences June 2021
Rilpivirine (TMC278, Edurant) Janssen Research & Development July 2024
Sofosbuvir/Velapatasvir (Epclusa) Gilead July 2016
Sutezolid - New - New Global Alliance for TB Drug Development (TB Alliance) April 2025
TBI-223 Global Alliance for TB Drug Development (TB Alliance) October 2023
Tecovirimat (TPOXX) SIGA Technologies, Inc. January 2025
Tenofovir Conrad November 2024
Vorinostat (Zolinza) Merck August 2013

Vaccines

Vaccine Name Sort descending Vaccine Company IB Date Risk List Available?
10-1074-LS(-J) Rockefeller University/Celldex Therapeutics November 2024
16055 NFL Delta Gly4 Env Protein Trimer, Adjuvanted with 3M-052 AF + Alum DAIDS/NIAID/NIH December 2023
3BNC117-LS (-J) Rockefeller University/Celldex Therapeutics November 2024
3M-052-AF Access to Advanced Health Institute (AAHI) November 2023
426c.Mod.Core-C4b, Adjuvanted - New - New DAIDS/NIAID/NIH January 2025
AdC6-HIVgp140, AdC7-HIVgp140, CH505TF/GLA-SE Vaccines DAIDS/NIAID/NIH March 2021
BG505 SOSIP.664 gp140 DAIDS/NIAID/NIH April 2024
BG505 SOSIP.GT1.1 gp140 Vaccine International AIDS Vaccine Initiative (IAVI) January 2024
CD40.HIVRI.Env (VRIPRO) - New - New Vaccine Research Institute (VRI) November 2024
CD4BS CH505M5 Pr-NP1, Adjuvanted DAIDS/NIAID/NIH April 2024
CH505 TF chTrimer - New - New DAIDS/NIAID/NIH May 2025
CH505M5 N197D mRNA-gp160 and CH505 TF mRNA-gp160 Duke Human Vaccine Institute (DHVI) November 2024
ChAdOx1.HIVconsv62 University of Oxford May 2024
ChAdOx1.tHIVconsv1 University of Oxford December 2024
CMV-MVA Triplex - New - New City of Hope National Medical Center October 2024
DV700P-RNA and DV701B1.1-RNA - New - New Duke Human Vaccine Institute (DHVI) February 2025
EnvSeq-1 and EnvSeq-2 DAIDS/NIAID/NIH October 2022
GLA-SE Infectious Disease Research Institute (IDRI) May 2023
GS-2872 (10-1074 LS) - New - New Gilead Sciences January 2025
GS-5423 (3BNC117-LS) - New - New Gilead Sciences January 2025