Investigator's Brochure (IB) Table

Drugs

Drug Name Sort descending Drug Company IB Date Risk List Available?
ABT-267, ABT 333, ABT-450 and Ritonavir AbbVie June 2017
Bedaquiline (TMC207) Janssen Research & Development October 2025
Delamanid (OPC-67683) Otsuka August 2024
Dolutegravir (GSK1349572) ViiV Healthcare October 2025
Emtricitabine/Tenofovir Disoproxil Fumarate (Truvada) Gilead Sciences December 2016 YES
Glecaprevir/Pibrentasvir AbbVie December 2025
GSK1265744 (Cabotegravir) - New ViiV Healthcare January 2026
Pretomanid (PA-824) - New Global Alliance for TB Drug Development (TB Alliance) December 2025
Quercefit (Quercetin Phospholipid) Indena February 2025
Remdesivir (Veklury) Gilead Sciences June 2021
Rilpivirine (TMC278, Edurant) Janssen Research & Development June 2025
Sutezolid Global Alliance for TB Drug Development (TB Alliance) April 2025
TBI-223 Global Alliance for TB Drug Development (TB Alliance) October 2023
Tenofovir Conrad November 2024
Tenofovir Disoproxil Fumarate/Emtricitabine/Levonorgestrel/ Ethinyl estradiol (Ahana) Viatris August 2024
Vorinostat (Zolinza) Merck August 2013

Vaccines

Vaccine Name Sort descending Vaccine Company IB Date Risk List Available?
HxB2.WT.Core-C4b, Adjuvanted DAIDS/NIAID/NIH October 2024
ID93 + GLA Adjuvant Vaccine AAHI May 2025
mRNA-1574 Trimer Vaccines DAIDS/NIAID/NIH November 2024
mRNA-1645-eODGT8 and mRNA-1645-CoreG28v2 Moderna October 2024
mRNA-1645-N332GT5 Moderna October 2024
MTBVAC Biofabri July 2024
MVA.tHIVconsv3 Vaccine University of Oxford May 2025
MVA.tHIVconsv4 Vaccine University of Oxford May 2025
N-803 Altor BioScience (ImmunityBio) December 2023
N332-GT5 gp140, Adjuvanted with SMNP DAIDS/NIAID/NIH July 2025
PGDM1400LS (VRC-HIVMAB0112-00-AB) DAIDS/NIAID/NIH March 2025
PGT121 Beth Israel Deaconess Medical Center September 2020
PGT121.414.LS (VRC-HIVMAB0107-00-AB) VCMP/NIAID/NIH June 2023
Poly-ICLC (Hiltonol) Oncovir, Inc. January 2025
Poly-ICLC (Hiltonol) Oncovir, Inc. July 2025
Selgantolimod (GS-9688) - New Gilead December 2024
Selgantolimod (GS-9688) - New Gilead January 2026
UVAX-1197 / UVAX-1107 Uvax Bio LLC January 2025
V3G CH848 Pr-NP1, Adjuvanted V3G CH848 mRNA-Tr2 and DV702B2-RNA - New VRC/NIAID/NIH January 2026
Vesatolimod (GS-9620) Gilead April 2025