The Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events consists of parameters, or Adverse Events (AEs), with severity grading guidance that are to be used in DAIDS clinical trials for safety data reporting to maintain accuracy and consistency in the evaluation of AEs.
Below are the Grading Tables (Versions 1.0, 2.0 and Corrected v 2.1), ​suggested citations, applicable clarification documents, and additional resources. The protocol will specify which DAIDS Adverse Event Grading Table is applicable.
DAIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Corrected Version 2.1
Suggested Citation
U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Division of AIDS. Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events, Corrected Version 2.1. [July 2017]. Available from: https://rsc.niaid.nih.gov/sites/default/files/daidsgradingcorrectedv21.pdf
DAIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 2.0
Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events (Version 2.0 - November 2014)
Suggested Citation
U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Division of AIDS. Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 2.0. [November 2014]. Available from: https://rsc.niaid.nih.gov/sites/default/files/daids-ae-grading-table-v2-nov2014.pdf
Clarification Documents for the DAIDS Table for Grading the Severity of Adult and Pediatric Adverse Events - Version 2.0 - November 2014
- Grading Table with all Changes Highlighted
- High Level Summary of Changes
- Parameter Level Summary of Changes
DAIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 1.0
Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events (Version 1.0 - December 2004 (Clarification dated August 2009))
Suggested Citation
U.S. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Division of AIDS. Division of AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events, Version 1.0. [Updated August 2009]. Available from: https://rsc.niaid.nih.gov/sites/default/files/table-for-grading-severity-of-adult-pediatric-adverse-events.pdf
Additional Grading Table Resources
- Addendum 1 - Female Genital Grading Table for Use in Microbicide Studies, Version 1.0 - November 2007
- Addendum 2 - Male Genital Grading Table for Use in Microbicide Studies, Version 1.0 - November 2007
- Addendum 3 - Rectal Grading Table for Use in Microbicide Studies (Clarification dated May 2012), Version 1.0 - November 2007
- Memo Regarding the Clarification to the Rectal Grading Table for Use in Microbicide Studies